Extracellular Matrix-Specific Platelet Activation Leads to a Differential Translational Response and Protein De Novo Synthesis in Human Platelets

Extracellular Matrix-Specific Platelet Activation Leads to a Differential Translational Response and Protein De Novo Synthesis in Human Platelets

Platelets are exposed to extracellular matrix (ECM) proteins like collagen and laminin and to fibrinogen during acute vascular events. However, beyond hemostasis, platelets have the important capacity to migrate on ECM surfaces, but the translational response of platelets to different extracellular...

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Bibliographic Details
Main Authors: Bjoern F. Kraemer, Marc Geimer, Mirita Franz-Wachtel, Tobias Lamkemeyer, Hanna Mannell, Stephan Lindemann
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
platelets
translation
extracellular matrix
differential protein expression
cytoskeleton
Online Access:https://www.mdpi.com/1422-0067/21/21/8155

Internet

https://www.mdpi.com/1422-0067/21/21/8155

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