Effect of PPARγ Inhibition during Pregnancy on Posterior Cerebral Artery Function and Structure

Peroxisome proliferator-activated receptor-γ (PPARγ), a ligand-activated transcription factor, has protective roles in the cerebral circulation, and, is highly activated during pregnancy. Thus, we hypothesized that PPARγ is involved in the adaptation of cerebral vasculature to pregnancy. Nonpregnant...

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Bibliographic Details
Main Authors: Siu-Lung eChan, Abbie C. Chapman, Julie G. Sweet, Natalia I. Gokina, Marilyn J Cipolla
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2010.00130/full