The number and transmission of [PSI] prion seeds (Propagons) in the yeast Saccharomyces cerevisiae.

BACKGROUND:Yeast (Saccharomyces cerevisiae) prions are efficiently propagated and the on-going generation and transmission of prion seeds (propagons) to daughter cells during cell division ensures a high degree of mitotic stability. The reversible inhibition of the molecular chaperone Hsp104p by gua...

Full description

Bibliographic Details
Main Authors: Lee J Byrne, Diana J Cole, Brian S Cox, Martin S Ridout, Byron J T Morgan, Mick F Tuite
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2650407?pdf=render