Effects of sildenafil and calcitonin gene-related peptide on brainstem glutamate levels: a pharmacological proton magnetic resonance spectroscopy study at 3.0 T

Effects of sildenafil and calcitonin gene-related peptide on brainstem glutamate levels: a pharmacological proton magnetic resonance spectroscopy study at 3.0 T

Abstract Background Studies involving human pharmacological migraine models have predominantly focused on the vasoactive effects of headache-inducing drugs, including sildenafil and calcitonin gene-related peptide (CGRP). However, the role of possible glutamate level changes in the brainstem and tha...

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Bibliographic Details
Main Authors: Samaira Younis, Anders Hougaard, Casper Emil Christensen, Mark Bitsch Vestergaard, Esben Thade Petersen, Olaf Bjarne Paulson, Henrik Bo Wiberg Larsson, Messoud Ashina
Format: Article
Language:English
Published: BMC 2018-06-01
Series:The Journal of Headache and Pain
Subjects:
MRS
Glutamate
Glx
Lactate
Migraine
Brainstem
Online Access:http://link.springer.com/article/10.1186/s10194-018-0870-2

Internet

http://link.springer.com/article/10.1186/s10194-018-0870-2

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