Strikingly Different Atheroprotective Effects of Apolipoprotein A-I in Early- Versus Late-Stage Atherosclerosis

Strikingly Different Atheroprotective Effects of Apolipoprotein A-I in Early- Versus Late-Stage Atherosclerosis

Summary: Preclinical studies have shown benefit of apolipoprotein A-I (apoA-I)/high-density lipoprotein (HDL) raising in atherosclerosis; however, this has not yet translated into a successful clinical therapy. Our studies demonstrate that apoA-I raising is more effective at reducing early-stage ath...

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Bibliographic Details
Main Authors: Jamie Morton, MBBS, PhD, Shisan Bao, MD, PhD, Laura Z. Vanags, BSc, PhD, Tania Tsatralis, BSc, Anisyah Ridiandries, BSc, PhD, Chung-Wah Siu, MBBS, MD, Kwong-Man Ng, BSc, PhD, Joanne T.M. Tan, BSc, PhD, David S. Celermajer, MBBS, PhD, Martin K.C. Ng, MBBS, PhD, Christina A. Bursill, BSc, PhD
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X17302838

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http://www.sciencedirect.com/science/article/pii/S2452302X17302838

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