Synthesis and Anticancer Activity of Some Novel Tetralin-6-yl-pyrazoline, 2-Thioxopyrimidine, 2-Oxopyridine, 2-Thioxo-pyridine and 2-Iminopyridine Derivatives

The title compounds were prepared by reaction of 6-acetyltetralin (1) with different aromatic aldehydes 2a-c, namely 2,6-dichlorobenzaldehyde, 2,6-diflouro-benzaldehyde, and 3-ethoxy-4-hydroxybenzaldehyde, to yield the corresponding a,b-unsaturated ketones 3a-c. Compound 3b was reacted with hydrazin...

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Bibliographic Details
Main Author: Ebtehal S. Al-Abdullah
Format: Article
Language:English
Published: MDPI AG 2011-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/4/3410/