Disease Activity-Associated Alteration of mRNA m5 C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus

Disease Activity-Associated Alteration of mRNA m5 C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus

Epigenetic processes including RNA methylation, post-translational modifications, and non-coding RNA expression have been associated with the heritable risks of systemic lupus erythematosus (SLE). In this study, we aimed to explore the dysregulated expression of 5-methylcytosine (m5C) in CD4+ T cell...

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Bibliographic Details
Main Authors: Gangqiang Guo, Huijing Wang, Xinyu Shi, Lele Ye, Kejing Yan, Zhiyuan Chen, Huidi Zhang, Zibing Jin, Xiangyang Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
systemic lupus erythematosus
CD4+ T cell
epigenetics
5-methylcytosine (m5C)
NSUN2
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00430/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00430/full

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