Data formats for modelling the spatial structure of chromatin based on experimental positions of nucleosomes

In the nucleus of eukaryotic cells, DNA is wrapped around histone proteins, forming units termed nucleosomes. Nucleosome chains fold into chromatin. Despite extensive experimental advancement, many fundamental features of chromatin remain uncertain. Since all cell types and states cannot be profiled...

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Bibliographic Details
Main Authors: Michael-Christian Mörl, Tilo Zülske, Robert Schöpflin, Gero Wedemann
Format: Article
Language:English
Published: AIMS Press 2019-05-01
Series:AIMS Biophysics
Subjects:
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Online Access:https://www.aimspress.com/article/10.3934/biophy.2019.3.83/fulltext.html