Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis

Lymphatic filariasis and onchocerciasis are debilitating diseases caused by parasitic filarial nematodes infecting around 150 million people throughout the tropics with more than 1.5 billion at risk. As with other neglected tropical diseases, classical drug-discovery and development is lacking and...

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Bibliographic Details
Main Authors: Kelly L. Johnston, Louise Ford, Indira Umareddy, Simon Townson, Sabine Specht, Kenneth Pfarr, Achim Hoerauf, Ralf Altmeyer, Mark J. Taylor
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320714000244