The association of Lewy bodies with limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes and their role in cognition and Alzheimer’s dementia in older persons

The association of Lewy bodies with limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes and their role in cognition and Alzheimer’s dementia in older persons

Abstract Lewy bodies (LBs) and limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) are common in older persons and associated with cognitive impairment. However, little is known about the relationship between LBs and LATE-NC and their combined roles in cognitive imp...

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Bibliographic Details
Main Authors: Sonal Agrawal, Lei Yu, Sukriti Nag, Konstantinos Arfanakis, Lisa L. Barnes, David A. Bennett, Julie A. Schneider
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Acta Neuropathologica Communications
Subjects:
Limbic-predominant age-related TDP-43 encephalopathy
Lewy bodies
Aging
Cognition
Alzheimer’s dementia
Online Access:https://doi.org/10.1186/s40478-021-01260-0

Internet

https://doi.org/10.1186/s40478-021-01260-0

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