N6-Adenosine Methylation of miRNA-200b-3p Influences Its Functionality and Is a Theranostic Tool

N6-Adenosine Methylation of miRNA-200b-3p Influences Its Functionality and Is a Theranostic Tool

MicroRNAs (miRNAs or miRs) play crucial roles in biological and pathological processes. Some miRNAs also appear as promising biomarkers and therapeutic tools. However, the epitranscriptomic regulation of miRNAs is not yet fully elucidated in all of their fields of application. We report that adenosi...

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Bibliographic Details
Main Authors: Joséphine Briand, Aurélien A. Sérandour, Arulraj Nadaradjane, Gwenola Bougras-Cartron, Dominique Heymann, Benjamin Ory, François M. Vallette, Pierre-François Cartron
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
miRNA methylation
glioblastoma
adenosine methylation
prodrug
biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120302390

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http://www.sciencedirect.com/science/article/pii/S2162253120302390

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