A New and Efficient Method for the Synthesis of 3,4-Disubstituted Pyrrolidine-2,5-diones

A newly found reaction for the synthesis of 3,4-disubstituted 1-hydroxy-pyrrolidine-2,5-diones from 3-substituted coumarins and nitromethane has been elaborated. The reaction involved a simple and convenient experimental procedure. The applicability of the rearrangement reaction is determined.

Bibliographic Details
Main Authors: Rositca D. Nikolova, Nevena I. Petkova, Eleonora D. Ilieva
Format: Article
Language:English
Published: MDPI AG 2012-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/5/4936