The Design and Synthesis of a New Class of RTK/HDAC Dual-Targeted Inhibitors

Over the years, the development of targeted medicines has made significant achievements. As a typical example, receptor tyrosine kinases (RTK) inhibitors have become important chemotherapy drugs for a variety of cancers. However, the effectiveness of these agents is always hindered by poor response...

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Bibliographic Details
Main Authors: Wei Lu, Jia Li, Xuan Zhang, Yi Chen, Mingbo Su
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/6/6491