3′-Terminated Overhangs Regulate DNA Double-Strand Break Processing in Escherichia coli

3′-Terminated Overhangs Regulate DNA Double-Strand Break Processing in Escherichia coli

Double-strand breaks (DSBs) are lethal DNA lesions, which are repaired by homologous recombination in Escherichia coli. To study DSB processing in vivo, we induced DSBs into the E. coli chromosome by γ-irradiation and measured chromosomal degradation. We show that the DNA degradation is regulated by...

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Bibliographic Details
Main Authors: Edyta Đermić, Davor Zahradka, Dušica Vujaklija, Siniša Ivanković, Damir Đermić
Format: Article
Language:English
Published: Oxford University Press 2017-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
DNA degradation
exonuclease activity
RecA protein
single-strand-specific exonucleases
recB1080 mutant
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.043521

Internet

http://g3journal.org/lookup/doi/10.1534/g3.117.043521

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