Role of Foxo1 gene expression in mechanism of antihypertrophic action of metformin in cardiomyocytes

Background. Diabetic cardiomyopathy is the leading cause of mortality in patients with type 2 diabetes mellitus. Hypertrophy of cardiomyocytes is one of the main pathomorphological signs of diabetic cardiomyopathy development. Metformin, the first-line drug for the treatment of type 2 diabetes melli...

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Bibliographic Details
Main Authors: N.V. Pasiechko, H.Ya. Loi, M.M. Korda, O.M. Oleshchuk
Format: Article
Language:English
Published: Publishing House Zaslavsky 2018-10-01
Series:Mìžnarodnij Endokrinologìčnij Žurnal
Subjects:
Online Access:http://iej.zaslavsky.com.ua/article/view/148779