Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury

Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury

Abstract Background Optic nerve injury is an important pathological component in neurodegenerative diseases such as traumatic optic neuropathies and glaucoma. The molecular signaling pathway(s) critical for retinal ganglion cell (RGC) death after axonal insult, however, is/are not fully defined. RGC...

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Bibliographic Details
Main Authors: Stephanie B. Syc-Mazurek, Kimberly A. Fernandes, Michael P. Wilson, Peter Shrager, Richard T. Libby
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Molecular Neurodegeneration
Subjects:
Axonopathy
Neurodegeneration
Retinal ganglion cell
Mitogen-activated protein kinase
Endoplasmic reticulum stress
Online Access:http://link.springer.com/article/10.1186/s13024-017-0214-8

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http://link.springer.com/article/10.1186/s13024-017-0214-8

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