Evaluation of the Expression Profile of Irinotecan-Induced Diarrhea in Patients with Colorectal Cancer

Irinotecan (CPT-11) is widely used for the treatment of unresectable colorectal cancer in combination with fluoropyrimidines, such as 5-fluorouracil and S-1. Diarrhea is one of the adverse effects associated with CPT-11 and frequently reported by patients treated with CPT-11-containing regimens comb...

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Bibliographic Details
Main Authors: Mashiro Okunaka, Daisuke Kano, Reiko Matsui, Toshikatsu Kawasaki, Yoshihiro Uesawa
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceuticals
Subjects:
S-1
Online Access:https://www.mdpi.com/1424-8247/14/4/377