Global Developmental Gene Programing Involves a Nuclear Form of Fibroblast Growth Factor Receptor-1 (FGFR1).

Global Developmental Gene Programing Involves a Nuclear Form of Fibroblast Growth Factor Receptor-1 (FGFR1).

Genetic studies have placed the Fgfr1 gene at the top of major ontogenic pathways that enable gastrulation, tissue development and organogenesis. Using genome-wide sequencing and loss and gain of function experiments the present investigation reveals a mechanism that underlies global and direct gene...

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Bibliographic Details
Main Authors: Christopher Terranova, Sridhar T Narla, Yu-Wei Lee, Jonathan Bard, Abhirath Parikh, Ewa K Stachowiak, Emmanuel S Tzanakakis, Michael J Buck, Barbara Birkaya, Michal K Stachowiak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4414453?pdf=render

Internet

http://europepmc.org/articles/PMC4414453?pdf=render

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