Increased adipogenesis in cultured embryonic chondrocytes and in adult bone marrow of dominant negative Erg transgenic mice.

Increased adipogenesis in cultured embryonic chondrocytes and in adult bone marrow of dominant negative Erg transgenic mice.

In monolayer culture, primary articular chondrocytes have an intrinsic tendency to lose their phenotype during expansion. The molecular events underlying this chondrocyte dedifferentiation are still largely unknown. Several transcription factors are important for chondrocyte differentiation. The Ets...

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Bibliographic Details
Main Authors: Sébastien Flajollet, Tian V Tian, Ludovic Huot, Nathalie Tomavo, Anne Flourens, Muriel Holder-Espinasse, Marion Le Jeune, Patrick Dumont, David Hot, Frédéric Mallein-Gerin, Martine Duterque-Coquillaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3498236?pdf=render

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http://europepmc.org/articles/PMC3498236?pdf=render

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