Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci

Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci

Genomic polymorphisms affect the epigenome, which in turn influences how epigenome- and genome-wide analysis are interpreted. Here, the authors characterise allelic differences in DNA methylation driven by obligatory or facilitative genetic effects, which may affect disease-related loci.

Bibliographic Details
Main Authors: Christopher G. Bell, Fei Gao, Wei Yuan, Leonie Roos, Richard J. Acton, Yudong Xia, Jordana Bell, Kirsten Ward, Massimo Mangino, Pirro G. Hysi, Jun Wang, Timothy D. Spector
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01586-1

Internet

https://doi.org/10.1038/s41467-017-01586-1

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