HIV-1 phenotypic reverse transcriptase inhibitor drug resistance test interpretation is not dependent on the subtype of the virus backbone.

HIV-1 phenotypic reverse transcriptase inhibitor drug resistance test interpretation is not dependent on the subtype of the virus backbone.

To date, the majority of HIV-1 phenotypic resistance testing has been performed with subtype B virus backbones (e.g. HXB2). However, the relevance of using this backbone to determine resistance in non-subtype B HIV-1 viruses still needs to be assessed. From 114 HIV-1 subtype C clinical samples (36 A...

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Bibliographic Details
Main Authors: Michelle Bronze, Kim Steegen, Carole L Wallis, Hans De Wolf, Maria A Papathanasopoulos, Margriet Van Houtte, Wendy S Stevens, Tobias Rinke de Wit, Lieven J Stuyver, ART-A Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3322145?pdf=render

Internet

http://europepmc.org/articles/PMC3322145?pdf=render

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