H3K27 modifiers regulate lifespan in C. elegans in a context-dependent manner
Abstract Background Evidence of global heterochromatin decay and aberrant gene expression in models of physiological and premature ageing have long supported the “heterochromatin loss theory of ageing”, which proposes that ageing is aetiologically linked to, and accompanied by, a progressive, genera...
Main Authors: | Abigail R. R. Guillermo, Karolina Chocian, Gavriil Gavriilidis, Julien Vandamme, Anna Elisabetta Salcini, Jane Mellor, Alison Woollard |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
|
Series: | BMC Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12915-021-00984-8 |
Similar Items
-
Automation of C. elegans lifespan measurement
by: Daniel P. Felker, et al.
Published: (2020-01-01) -
Germline burden of rare damaging variants negatively affects human healthspan and lifespan
by: Anastasia V Shindyapina, et al.
Published: (2020-04-01) -
Mitochondrial DNA Damage Does Not Determine C. elegans Lifespan
by: Li Fang Ng, et al.
Published: (2019-04-01) -
Healthspan Enhancement by Olive Polyphenols in <i>C. elegans</i> Wild Type and Parkinson’s Models
by: Gabriele Di Rosa, et al.
Published: (2020-05-01) -
Healthspan Maintenance and Prevention of Parkinson’s-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in <i>C. elegans</i>
by: Giovanni Brunetti, et al.
Published: (2020-04-01)