Type I interferons are essential while type II interferon is dispensable for protection against St. Louis encephalitis virus infection in the mouse brain

Type I interferons are essential while type II interferon is dispensable for protection against St. Louis encephalitis virus infection in the mouse brain

St. Louis encephalitis virus (SLEV) is a neglected mosquito-borne flavivirus that causes severe neurological disease in humans. SLEV replication in the central nervous system (CNS) induces the local production of interferons (IFNs), which are attributed to host protection. The antiviral response to...

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Bibliographic Details
Main Authors: Rebeca Froes Rocha, Juliana L. Del Sarto, Giovanni F. Gomes, Mariana P. Gonçalves, Milene A. Rachid, Juliana H. C. Smetana, Daniele G. Souza, Mauro Martins Teixeira, Rafael Elias Marques
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Virulence
Subjects:
neglected arbovirus
flavivirus
st. louis encephalitis
interferons
mouse model
Online Access:http://dx.doi.org/10.1080/21505594.2020.1869392

Internet

http://dx.doi.org/10.1080/21505594.2020.1869392

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