A synthetic probiotic engineered for colorectal cancer therapy modulates gut microbiota

A synthetic probiotic engineered for colorectal cancer therapy modulates gut microbiota

Abstract Background Successful chemoprevention or chemotherapy is achieved through targeted delivery of prophylactic agents during initial phases of carcinogenesis or therapeutic agents to malignant tumors. Bacteria can be used as anticancer agents, but efforts to utilize attenuated pathogenic bacte...

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Bibliographic Details
Main Authors: Yusook Chung, Yongku Ryu, Byung Chull An, Yeo-Sang Yoon, Oksik Choi, Tai Yeub Kim, Jaekyung Yoon, Jun Young Ahn, Ho Jin Park, Soon-Kyeong Kwon, Jihyun F. Kim, Myung Jun Chung
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Microbiome
Subjects:
Lactobacillus rhamnosus CBT LR5 (KCTC 12202BP)
Alanine racemase
DLD-1 xenograft
AOM/DSS model of colitis-associated cancer
Microbiome
Akkermansia
Online Access:https://doi.org/10.1186/s40168-021-01071-4

Internet

https://doi.org/10.1186/s40168-021-01071-4

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