Curcumin inhibits activation of TRPM2 channels in rat hepatocytes

Oxidative stress is a hallmark of many liver diseases including viral and drug-induced hepatitis, ischemia-reperfusion injury, and non-alcoholic steatohepatitis. One of the consequences of oxidative stress in the liver is deregulation of Ca2+ homeostasis, resulting in a sustained elevation of the fr...

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Bibliographic Details
Main Authors: E. Kheradpezhouh, G.J. Barritt, G.Y. Rychkov
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231715300021