Ellagic Acid Prevents L-NAME-Induced Hypertension via Restoration of eNOS and p47phox Expression in Rats

Ellagic Acid Prevents L-NAME-Induced Hypertension via Restoration of eNOS and p47phox Expression in Rats

The effect of ellagic acid on oxidative stress and hypertension induced by Nω-Nitro-l-arginine methyl ester hydrochloride (L-NAME) was investigated. Male Sprague-Dawley rats were administrated with L-NAME (40 mg/kg/day) for five weeks. L-NAME induced high systolic blood pressure (SBP) and increase...

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Bibliographic Details
Main Authors: Thewarid Berkban, Pattanapong Boonprom, Sarawoot Bunbupha, Jariya Umka Welbat, Upa Kukongviriyapan, Veerapol Kukongviriyapan, Poungrat Pakdeechote, Parichat Prachaney
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Nutrients
Subjects:
ellagic acid
high blood pressure
nitric oxide deficiency
NADPH oxidase
antioxidant
Online Access:http://www.mdpi.com/2072-6643/7/7/5222

Internet

http://www.mdpi.com/2072-6643/7/7/5222

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