Pharmacokinetics and Excretion of Berberine and Its Nine Metabolites in Rats

Berberine, a well-known alkaloid, has been proved to possess various pharmacological activities. Previous studies demonstrated that berberine could be extensively metabolized and the metabolites also contributed to its therapeutic effects. However, as for berberine’s metabolites, especially phase II...

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Bibliographic Details
Main Authors: Xinchi Feng, Kun Wang, Shijie Cao, Liqin Ding, Feng Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.594852/full