A molecular switch orchestrates enzyme specificity and secretory granule morphology

Regulated secretion is an essential process that requires packing and maturation of cargo proteins in membranous secretory granules. Here, authors identify a gene, pgant9, that influences the glycosylation status of the secretory cargo as well as the structure of secretory granules within the Drosop...

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Bibliographic Details
Main Authors: Suena Ji, Nadine L. Samara, Leslie Revoredo, Liping Zhang, Duy T. Tran, Kayla Muirhead, Lawrence A. Tabak, Kelly G. Ten Hagen
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05978-9