Glucocorticoids influence versican and chondroitin sulphate proteoglycan levels in the fetal sheep lung

Glucocorticoids influence versican and chondroitin sulphate proteoglycan levels in the fetal sheep lung

Abstract Background Prenatal glucocorticoid treatment decreases alveolar tissue volumes and facilitates fetal lung maturation, however the mechanisms responsible are largely unknown. This study examines whether changes in versican levels or sulphation patterns of chondroitin sulphate (CS) side chain...

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Bibliographic Details
Main Authors: Annie R. A. McDougall, Amanda J. Fosang, Jessica Faggian, Megan J. Wallace, Kelly J. Crossley, Timothy J. Cole, Stuart B. Hooper
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Respiratory Research
Subjects:
Cortisol
Betamethasone
Lung development
Extracellular matrix
Adrenalectomy
Online Access:http://link.springer.com/article/10.1186/s12931-018-0854-4

Internet

http://link.springer.com/article/10.1186/s12931-018-0854-4

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