Dynamic mechanism of multiple bursting patterns in a whole-cell multiscale model with calcium oscillations

The dynamic mechanism of a whole-cell model containing electrical signalling and two-compartment Ca $ ^{2+} $ signalling in gonadotrophs is investigated. The transition from spiking to bursting by Hopf bifurcation of the fast subsystem about the slow variable is detected via the suitable parameters....

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Bibliographic Details
Main Authors: Xiaowen Xiong, Yanqiu Li, Dongmei Zheng
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Journal of Biological Dynamics
Subjects:
Online Access:http://dx.doi.org/10.1080/17513758.2021.1925753