Predicting genetic interactions with random walks on biological networks

<p>Abstract</p> <p>Background</p> <p>Several studies have demonstrated that synthetic lethal genetic interactions between gene mutations provide an indication of functional redundancy between molecular complexes and pathways. These observations help explain the finding...

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Bibliographic Details
Main Authors: Singh Ambuj K, Chipman Kyle C
Format: Article
Language:English
Published: BMC 2009-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/10/17