Humanin Rescues Cultured Rat Cortical Neurons from NMDA-Induced Toxicity Not by NMDA Receptor

Excitatory neurotoxicity has been implicated in many pathological situations and there is no effective treatment available. Humanin is a 24-aa peptide cloned from the brain of patients with Alzheimer’s disease (AD). In the present study, excitatory toxicity was induced by N-methyl-D-aspartate (NMDA)...

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Bibliographic Details
Main Authors: Ai-Ling Cui, Jian-Zhong Li, Zhi-Bo Feng, Guo-Lin Ma, Liang Gong, Chun-Ling Li, Ce Zhang, Kefeng Li
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/341529