Differential Effects of E2 on MAPK Activity in the Brain and Heart of Aged Female Rats.

Aging and the coincident loss of circulating estrogens at menopause lead to increased risks for neurological and cardiovascular pathologies. Clinical studies show that estrogen therapy (ET) can be beneficial in mitigating these negative effects, in both the brain and heart, when it is initiated shor...

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Bibliographic Details
Main Authors: Elena Pinceti, Cody L Shults, Yathindar S Rao, Toni R Pak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4972350?pdf=render