Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid
Phosphatidylinositol (3–5) trisphosphate (PIP3) is a central regulator of diverse neuronal functions that are critical for seizure progression, however its role in seizures is unclear. We have recently hypothesised that valproic acid (VPA), one of the most commonly used drugs for the treatment of ep...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-02-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996113002921 |