TMEM180 contributes to SW480 human colorectal cancer cell proliferation through intra-cellular metabolic pathways

TMEM180, a novel colon cancer–specific protein with a 12-transmembrane topology, is upregulated at low oxygen. Previously, we established a humanized monoclonal antibody against TMEM180 aimed at clinical trials. Prior to such trials, it is necessary to clarify the function of TMEM180 in cancer. To c...

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Bibliographic Details
Main Authors: Takahiro Anzai, Shinji Saijou, Yoshitsugu Ohnuki, Hiroshi Kurosawa, Masahiro Yasunaga, Yasuhiro Matsumura
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Translational Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321001789