Dynamic biochemical tissue analysis detects functional L-selectin ligands on colon cancer tissues.

Dynamic biochemical tissue analysis detects functional L-selectin ligands on colon cancer tissues.

A growing body of evidence suggests that L-selectin ligands presented on circulating tumor cells facilitate metastasis by binding L-selectin presented on leukocytes. Commonly used methods for detecting L-selectin ligands on tissues, e.g., immunostaining, are performed under static, no-flow condition...

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Bibliographic Details
Main Authors: Grady E Carlson, Eric W Martin, Venktesh S Shirure, Ramiro Malgor, Vicente A Resto, Douglas J Goetz, Monica M Burdick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5345883?pdf=render

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http://europepmc.org/articles/PMC5345883?pdf=render

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