The screening and evaluation of potential clinically significant HIV drug combinations against the SARS-CoV-2 virus

The screening and evaluation of potential clinically significant HIV drug combinations against the SARS-CoV-2 virus

Spike glycoprotein is essential for the reproduction of the SARS-CoV-2 virus, and its inhibition using already approved antiviral drugs may open new avenues for treatment of patients with the COVID-19 disease. Because of that we analyzed the inhibition of SARS-CoV-2 spike glycoprotein with FDA-appro...

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Bibliographic Details
Main Authors: Draško Tomić, Davor Davidović, Attila Marcel Szasz, Melinda Rezeli, Boris Pirkić, Jozsef Petrik, Vesna Bačić Vrca, Vladimir Janđel, Tomislav Lipić, Karolj Skala, Josip Mesarić, Marija Milković Periša, Zorislav Šojat, Branka Medved Rogina
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Informatics in Medicine Unlocked
Subjects:
SARS-CoV-2 spike glycoprotein
HIV cocktail Therapy
Inhibition efficiency
Virtual drug screening
Antiviral drugs
COVID-19
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914821000198

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http://www.sciencedirect.com/science/article/pii/S2352914821000198

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