Defining the Thrombotic Risk in Patients with Myeloproliferative Neoplasms

Polycythemia vera (PV) and essential thrombocythemia (ET) are two Philadelphia-negative myeloproliferative neoplasms (MPN) associated with an acquired mutation in the JAK2 tyrosine kinase gene. There is a rare incidence of progression to myelofibrosis and myeloid metaplasia in both disorders, which...

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Bibliographic Details
Main Authors: Fabrizio Vianello, Anna Battisti, Giuseppe Cella, Marina Marchetti, Anna Falanga
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2011.108