Integrin Trafficking and Tumor Progression

Integrins are major mediators of cancer cell adhesion to extracellular matrix. Through this interaction, integrins play critical roles in cell migration, invasion, metastasis, and resistance to apoptosis during tumor progression. Recent studies highlight the importance of integrin trafficking, endoc...

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Bibliographic Details
Main Authors: Sejeong Shin, Laura Wolgamott, Sang-Oh Yoon
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2012/516789