Prioritisation and network analysis of Crohn's disease susceptibility genes.

Recent Genome-Wide Association Studies (GWAS) have revealed numerous Crohn's disease susceptibility genes and a key challenge now is in understanding how risk polymorphisms in associated genes might contribute to development of this disease. For a gene to contribute to disease phenotype, its ri...

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Bibliographic Details
Main Authors: Daniele Muraro, Douglas A Lauffenburger, Alison Simmons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182533?pdf=render