Microglial replacement therapy: a potential therapeutic strategy for incurable CSF1R-related leukoencephalopathy
Abstract CSF1R-related leukoencephalopathy is an adult-onset leukoencephalopathy with axonal spheroids and pigmented glia caused by colony stimulating factor 1 receptor (CSF1R) gene mutations. The disease has a global distribution and currently has no cure. Individuals with CSF1R-related leukoenceph...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-12-01
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Series: | Acta Neuropathologica Communications |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40478-020-01093-3 |