2′-O-Methyl-8-methylguanosine as a Z-Form RNA Stabilizer for Structural and Functional Study of Z-RNA

In contrast to Z-DNA that was stabilized and well-studied for its structure by chemical approaches, the stabilization and structural study of Z-RNA remains a challenge. In this study, we developed a Z-form RNA stabilizer m8Gm, and demonstrated that incorporation of m8Gm into RNA can markedly stabili...

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Bibliographic Details
Main Authors: Thananjeyan Balasubramaniyam, Takumi Ishizuka, Chao-Da Xiao, Hong-Liang Bao, Yan Xu
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
NMR
Online Access:http://www.mdpi.com/1420-3049/23/10/2572