Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis

Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis

Abstract Background Our previous report suggested that centrosomal P4.1-associated protein (CPAP) is required for Hepatitis B virus (HBV) encoded non-structure protein X (HBx)-mediated nuclear factor kappa light chain enhancer of activated B cells (NF-κB) activation. CPAP is overexpressed in HBV-ass...

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Bibliographic Details
Main Authors: Chia-Jui Yen, Shu-Ting Yang, Ruo-Yu Chen, Wenya Huang, Kazuaki Chayama, Ming-Hao Lee, Shiang-Jie Yang, Hong-Sheng Lai, Hsin-Yi Yen, Yu-Wei Hsiao, Ju-Ming Wang, Yih-Jyh Lin, Liang-Yi Hung
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Biomedical Science
Subjects:
Hepatocarcinogenesis
CPAP
HBx
NF-κB
Inflammation
Online Access:http://link.springer.com/article/10.1186/s12929-019-0534-9

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http://link.springer.com/article/10.1186/s12929-019-0534-9

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