The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes
The mechanisms generating epileptic neuronal networks following insults such as severe seizures are unknown. We have previously shown that interfering with the function of the neuron-restrictive silencer factor (NRSF/REST), an important transcription factor that influences neuronal phenotype, attenu...
Main Authors: | Shawn McClelland, Gary P Brennan, Celine Dubé, Seeta Rajpara, Shruti Iyer, Cristina Richichi, Christophe Bernard, Tallie Z Baram |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/01267 |
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