Renal clearable nanochelators for iron overload therapy

The build-up of iron in the body can have serious consequences; current treatment therapies suffer from adverse side effects and toxicity. Here, the authors developed renal clearable nanochelators with improved pharmacodynamics and demonstrated their efficacy and safety in iron overload animal model...

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Bibliographic Details
Main Authors: Homan Kang, Murui Han, Jie Xue, Yoonji Baek, JuOae Chang, Shuang Hu, HaYoung Nam, Min Joo Jo, Georges El Fakhri, Michael P. Hutchens, Hak Soo Choi, Jonghan Kim
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13143-z