Dietary restriction in the long-chain acyl-CoA dehydrogenase knockout mouse

Dietary restriction in the long-chain acyl-CoA dehydrogenase knockout mouse

Patients with a disorder of mitochondrial long-chain fatty acid β-oxidation (FAO) have reduced fasting tolerance and may present with hypoketotic hypoglycemia, hepatomegaly, (cardio)myopathy and rhabdomyolysis. Patients should avoid a catabolic state because it increases reliance on FAO as energy so...

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Bibliographic Details
Main Authors: Eugène F. Diekman, Michel van Weeghel, Mayte Suárez-Fariñas, Carmen Argmann, Pablo Ranea-Robles, Ronald J.A. Wanders, Gepke Visser, Ingeborg van der Made, Esther E. Creemers, Sander M. Houten
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Mouse model
Dietary restriction
Caloric restriction
Fatty acid oxidation
Cardiac function
Inborn error of metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426921000434

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http://www.sciencedirect.com/science/article/pii/S2214426921000434

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