RBP2 Promotes Adult Acute Lymphoblastic Leukemia by Upregulating BCL2.

Despite recent increases in the cure rate of acute lymphoblastic leukemia (ALL), adult ALL remains a high-risk disease that exhibits a high relapse rate. In this study, we found that the histone demethylase retinoblastoma binding protein-2 (RBP2) was overexpressed in both on-going and relapse cases...

Full description

Bibliographic Details
Main Authors: Xiaoming Wang, Minran Zhou, Yue Fu, Ting Sun, Jin Chen, Xuemei Qin, Yuan Yu, Jihui Jia, Chunyan Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4805198?pdf=render