Widespread recombination, reassortment, and transmission of unbalanced compound viral genotypes in natural arenavirus infections.

Arenaviruses are one of the largest families of human hemorrhagic fever viruses and are known to infect both mammals and snakes. Arenaviruses package a large (L) and small (S) genome segment in their virions. For segmented RNA viruses like these, novel genotypes can be generated through mutation, re...

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Bibliographic Details
Main Authors: Mark D Stenglein, Elliott R Jacobson, Li-Wen Chang, Chris Sanders, Michelle G Hawkins, David S-M Guzman, Tracy Drazenovich, Freeland Dunker, Elizabeth K Kamaka, Debbie Fisher, Drury R Reavill, Linda F Meola, Gregory Levens, Joseph L DeRisi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4438980?pdf=render