The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences

The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences

Molecular profiling of breast cancer in non-Caucasian populations remains underexplored. Here the authors report a high prevalence of HER2-subtypes and enriched immune score with improved survival and higher rates of TP53 somatic mutations with poorer survival in ER+ tumours in a Malaysian cohort.

Bibliographic Details
Main Authors: Jia-Wern Pan, Muhammad Mamduh Ahmad Zabidi, Pei-Sze Ng, Mei-Yee Meng, Siti Norhidayu Hasan, Bethan Sandey, Stephen-John Sammut, Cheng-Har Yip, Pathmanathan Rajadurai, Oscar M. Rueda, Carlos Caldas, Suet-Feung Chin, Soo-Hwang Teo
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20173-5

Internet

https://doi.org/10.1038/s41467-020-20173-5

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