MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer

Abstract MicroRNA-34 (miR-34) has been reported to be dysregulated in various human cancers and regarded as a tumor suppressive microRNA because of its synergistic effect with the well-known tumor suppressor p53. Along with the application of MRX34, the first tumor-targeted microRNA drug which based...

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Bibliographic Details
Main Authors: Lu Zhang, Yi Liao, Liling Tang
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
EMT
Online Access:http://link.springer.com/article/10.1186/s13046-019-1059-5